Urea , also known as cream containing carbamide , is used as a medicine and applied to the skin to treat dryness and itching as can occur in psoriasis, dermatitis, or ichthyosis.. It can also be used to smooth the nails.
In adults the side effects are generally slight. Sometimes it causes skin irritation. Urea works in part by loosening dry skin. Preparations generally contain 5 to 50% urea.
Creams containing urea have been used since the 1940s. It's in the WHO Essential Medicines List, the most effective and safe medication needed in the health system. It is available on the table. In the UK 100 g cream 10% NHS costs about 4.37 pounds.
Video Urea-containing cream
Medical use
Urea cream is indicated for the debridement and promotion of normal healing of skin areas with hyperkeratosis, especially where healing is inhibited by local skin infections, skin necrosis, fibrinous or itchy debris or eschar. Special conditions with hyperkeratosis where urea cream is useful include:
- Dry skin and rough skin
- Dermatitis
- Psoriasis
- Ichthyosis
- Eczema
- Keratosis
- Keratoderma
- Corn
- Callback
- Damaged, nails grow inward and obfuscated
Maps Urea-containing cream
Side effects
Common side effects of urea cream are:
- Light skin irritation
- Temporary burning sensation
- Stinging sensation
- Itch
In severe cases, there can be allergic reactions with symptoms such as skin rashes, urticaria, difficulty breathing and swelling of the mouth, face, lips, or tongue.
Action mechanism
Urea dissolves the intercellular matrix of stratum corneum cells, promotes scaly skin desquamation, eventually resulting in softening of the hyperkeratotic area. In the nail, urea causes softening and ultimately debridement of the nail plate.
References
Source of the article : Wikipedia
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